i3.1 Capsule 30's pack
+88 01336 242 801
-
Helax Tabler 50's pack
৳144.00 -
Enosperm Tablet 30 pcs
৳1,620.00 -
Glow Briss Face Wash 100 ml
৳1,081.00 -
Inosia-F Tablet 30 pcs
৳1,757.80 -
OSTE-Plus Tablet 30's pack
৳653.30
I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life
Abstract
Aim: To determine the dose-related effects of a novel probiotic combination, I.31, on irritable bowel syndrome (IBS)-related quality of life (IBS-QoL).
Methods: A multicenter, randomized, double-blind, placebo-controlled intervention clinical trial with three parallel arms was designed. A total of 84 patients (53 female, 31 male; age range 20-70 years) with IBS and diarrhea according to Rome-III criteria were randomly allocated to receive one capsule a day for 6 wk containing: (1) I.31 high dose (n = 28); (2) I.31 low dose (n = 27); and (3) placebo (n = 29). At baseline, and 3 and 6 wk of treatment, patients filled the IBSQoL, Visceral Sensitivity Index (VSI), and global symptom relief questionnaires.
Results: During treatment, IBS-QoL increased in all groups, but this increment was significantly larger in patients treated with I.31 than in those receiving placebo (P = 0.008). After 6 wk of treatment, IBS-QoL increased by 18 ± 3 and 22 ± 4 points in the high and the low dose groups, respectively (P = 0.041 and P = 0.023 vs placebo), but only 9 ± 3 in the placebo group. Gut-specific anxiety, as measured with VSI, also showed a significantly greater improvement after 6 wk of treatment in patients treated with probiotics (by 10 ± 2 and 14 ± 2 points, high and low dose respectively, P < 0.05 for both vs 7 ± 1 score increment in placebo). Symptom relief showed no significant changes between groups. No adverse drug reactions were reported following the consumption of probiotic or placebo capsules.
Conclusion: A new combination of three different probiotic bacteria was superior to placebo in improving IBS-related quality of life in patients with IBS and diarrhea.
Related products
Pregotin Tablet 30 pcs
Meniglow AG Tablet 20 pcs
INTEL-IQ Syrup 60 ml
ACT-D3 Drops 30 ml
MUM-Baby KID Drops 30 ml
Goodcal Syrup 150 ml
DHA 3plus Capsule 30 pcs
ZD Plus Drops 30 ml
Nova-IQ Syrup 100 ml
Amvital Drops 30 ml
Amcogermina Suspension 10 pcs (1 pkt)
Stonark 2.5 mg Tablet 30 pcs
Norfolet DS Tablet 24 pcs
HiCal Max Tablet 30 pcs
Legend-D3 Tablet 30 pcs
Gluthion-Cal Tablet 30 pcs
Glufast Capsule 30 pcs
NEOLAX Capsule 30 pcs
Resperm Tablet 30 pcs
Ovarzen Plus Tablet 30 pcs
Megagel 369 Capsule 30 pcs
Lurocum Tablet 30 pcs
Karkuma Joint Guard Capsule 90 pcs
GM Pro Tablet 30 pcs
Cal-Fil Tablet 30 pcs
Riva-KId Drops 30 ml
Spirutas Capsule 30 pcs
Pregna-Treat Tablet 30 pcs
OVA Flow Tablet 30 pcs
MYOTREAT Tablet 30 pcs
FERTIZEAL-M Tablet 30 pcs
FERTIZEAL-F Tablet 30 pcs
SYALOX 300 PLUS Tablet 20 pcs
Oxokal Sil Tablet 30 pcs
Nevralip 600 RTD Tablet 15 pcs
Epaset Tablet 30 pcs
Myopai Tablet 30 pcs
DA-Q10 Tablet 30 pcs
Anasone 100 (Dapsone 100 mg) Tablet 30 pcs
Pentasure HP Sachet 6 pcs
Pregnabest Tablet 30 pcs
Ferticon-75 Tablet 30 pcs
Willfert-M Tablet 30 pcs
Pathy DS Tablet 30 pcs
Logy DS Tablet 30 pcs
Omega 369 Forte Capsule 30 pcs
Neurobion-AZ Tablet 30 pcs
Multivit-AZ Capsule 30 pcs
DHEA Forte Capsule 30 pcs
Chirogest-60 Capsule 30 pcs
Contact Info
- Address: South Banasree, Rampura, Dhaka
- Phone: 01336 242 801
- Email: order@onlinestorebd.com
